Uric Acid As a Cardiovascular Risk Factor Or Not?
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چکیده
منابع مشابه
Uric acid and cardiovascular risk.
Copyright © 2008 Massachusetts Medical Society. An association of gout with hypertension, diabetes, kidney disease, and cardiovascular disease has been observed since the late 19th century. Early investigators, such as Frederick Mahomed, Alexander Haig, and Nathan Smith Davis, hypothesized that uric acid might be a cause of hypertension or renal disease. In 1897, in his presidential address to ...
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Uric acid (UA) is a potent endogenous antioxidant. However, high concentrations of this molecule have been associated with cardiovascular disease (CVD) and renal dysfunction, involving mechanisms that include oxidative stress, inflammatory processes, and endothelial injury. Experimental and in vitro results suggest that this biomarker behaves like other antioxidants, which can shift from the ph...
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BACKGROUND The predictive value of serum uric acid (SUA) for adverse cardiovascular events among obese and overweight patients is not known, but potentially important because of the relation between hyperuricaemia and obesity. METHODS The relationship between SUA and risk of cardiovascular adverse outcomes (nonfatal myocardial infarction, nonfatal stroke, resuscitated cardiac arrest or cardio...
متن کاملDoes uric acid qualify as an independent risk factor for cardiovascular mortality?
UA (uric acid) is the final product of purine metabolism in humans and is implicated in many disease conditions. Sustained hyperuricaemia has putative adverse roles in cardiovascular diseases. Despite strong evidence emerging from large epidemiological studies supporting the hypothesis that UA independently influences cardiovascular disease outcomes and mortality, a causal role is yet to be est...
متن کاملUric acid. A risk factor for coronary heart disease.
The association between serum uric acid and the prevalence of ECG abnormalities was analyzed for 24.997 employed men and women, white and black, age 18--64 years, from the Chicago Heart Association (CHA) Detection Project in Industry. In addition, the relationships between uric acid and 5-year mortality from all causes, from cardiovascular diseases (CVD), and from coronary heart disease (CHD) w...
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ژورنال
عنوان ژورنال: Angiology
سال: 2013
ISSN: 0003-3197,1940-1574
DOI: 10.1177/0003319713507770